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Calibrate — Clinical Nutrition Practice
87%
Hit Target Biomarkers
within 90 days of protocol start
1,400+
Lab Panels Reviewed
across cholesterol, metabolic & GI panels
12 yrs
Clinical Practice
functional & integrative nutrition

Results measured in bloodwork, not before-and-after photos.

Calibrate reads your lab panels the way a CFO reads a balance sheet — identifying the exact levers that move your numbers, then building a meal architecture around them.

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The Practice

Twelve years reading labs
that primary care didn't have time to explain.

Every consultation starts with your actual bloodwork. Not a food diary. Not a quiz about your stress levels. The numbers on the page — LDL particle size, fasting insulin, CRP, homocysteine — tell a specific story, and that story dictates the protocol.

RDNRegistered Dietitian Nutritionist
CNSCertified Nutrition Specialist
IFMCPInstitute for Functional Medicine
Philosophy
Most elimination diets treat every body the same. Your labs don't. A triglyceride-to-HDL ratio of 4.2 calls for a different intervention than a ratio of 1.8 — even if both patients describe the same symptoms.
8–12
weeks to measurable biomarker change
Zero
generic protocols — each plan is lab-derived
Clinical Case Studies

Real panels. Specific protocols.
Measured outcomes.

Each case below is documented from intake labs through 12-week follow-up. The interventions are specific, the numbers are real, and the protocol language is exactly what was prescribed — not a summary.

Case 01Cholesterol Management
Comprehensive Metabolic + Lipid Panel
Baseline — March 2025
Flagged
MarkerBeforeAfterRef.
LDL Cholesterolmg/dL
187112<100
HDL Cholesterolmg/dL
4158>60
Triglyceridesmg/dL
218131<150
hsCRPmg/L
3.40.9<1.0
Fasting Glucosemg/dL
1049170–99
Male, 47 — Software Director, Chicago

LDL 187 mg/dL. CRP 3.4. Primary care recommended a statin.

01

Restructured macronutrient timing around a 10-hour feeding window (8am–6pm), eliminating post-dinner insulin spikes that were suppressing overnight HDL synthesis.

02

Replaced refined seed oils (canola, sunflower) with extra-virgin olive oil and grass-fed tallow — reducing linoleic acid load from ~18g/day to under 4g.

03

Introduced fermented vegetables at two meals daily (kimchi at lunch, kefir at dinner) to shift bile acid metabolism via gut microbiome modulation.

04

Added 2g/day of plant sterols via specific food sources — not supplements — timed around the highest-fat meal.

12-Week Outcome

LDL reduced 40% to 112 mg/dL. hsCRP normalized to 0.9 mg/L. HDL rose 17 points. Triglycerides dropped 87 mg/dL. No statin required.

"I'd been told my cholesterol was 'genetic' for three years. Turns out it was a 6pm dinner with seed-oil stir-fry every night."
Client, Case 01 — 12-week follow-up

A1C 6.1%. Fasting insulin 22 μIU/mL. PCP prescribed Metformin.

01

Eliminated all liquid calories including "healthy" smoothies — identified as primary driver of post-breakfast insulin spikes via continuous glucose monitoring data.

02

Front-loaded protein to 40g at breakfast (eggs, sardines, Greek yogurt rotation) to blunt the cortisol-glucose spike that was elevating fasting readings.

03

Sequenced meals as fiber → fat → protein → carbohydrate to reduce peak glucose response by an average of 32% (validated via CGM over 6 weeks).

04

Addressed elevated ferritin through strategic phlebotomy referral and reduced red meat frequency — ferritin elevation was driving insulin resistance independently.

12-Week Outcome

A1C dropped to 5.4% in 11 weeks. Fasting insulin normalized to 7 μIU/mL. HOMA-IR fell from 5.7 to 1.6. Metformin not initiated.

"The smoothie I made every morning — spinach, banana, almond butter, oat milk — was spiking me to 165 mg/dL. No one had ever looked at that."
Client, Case 02 — 11-week follow-up
Case 02Pre-Diabetic A1C
Glucose + Insulin Resistance Panel
Baseline — October 2025
Flagged
MarkerBeforeAfterRef.
HbA1c%
6.15.4<5.7
Fasting InsulinμIU/mL
2272–6
HOMA-IRindex
5.71.6<2.0
Fasting Glucosemg/dL
1188970–99
Ferritinng/mL
31218912–150
Female, 52 — Ops Executive, Boston
Case 03Autoimmune Protocol
Thyroid + Autoimmune + Micronutrient Panel
Baseline — January 2026
Flagged
MarkerBeforeAfterRef.
TPO AntibodiesIU/mL
890312<35
TSHmIU/L
4.82.10.5–2.5
Zonulinng/mL
6728<22
Vitamin D (25-OH)ng/mL
196150–80
Seleniumμg/L
68134120–150
Female, 39 — Attorney, New York

Hashimoto's thyroiditis. TPO antibodies 890 IU/mL. Fatigue, GI permeability markers elevated.

01

Removed gluten and casein for 12 weeks — not permanently, but to assess intestinal permeability contribution to antibody production (zonulin as the objective measure, not symptom reporting).

02

Corrected selenium deficiency to 200mcg/day via Brazil nuts (2–3 daily) — selenium is the rate-limiting cofactor for thyroid peroxidase, directly implicated in antibody elevation.

03

Introduced bone broth and L-glutamine at 5g/day to repair intestinal tight junctions, validated at week 8 by re-testing zonulin.

04

Structured iodine intake carefully — excess iodine accelerates Hashimoto's progression; reduced high-iodine foods and standardized to 150mcg/day from whole food sources only.

12-Week Outcome

TPO antibodies reduced 65% to 312 IU/mL at 12 weeks. TSH normalized. Zonulin dropped to 28 ng/mL. Energy rated 8/10 vs. 3/10 at intake.

"Every rheumatologist told me diet wouldn't touch my antibody numbers. I have the labs that say otherwise."
Client, Case 03 — 12-week follow-up
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Book Your Lab Review

Upload your most recent labs or we'll order the right panel. The first review is complimentary — no pitch, no protocol sales. Just an honest read of your numbers.

Complimentary Review

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No commitment required. Initial review is complimentary.

87% hit target biomarkers in 90 days
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Response within 24 hours

Not ready to book? The guide below covers the five markers that most standard panels skip — and why they matter more than total cholesterol.

Free Download

The 5 Markers Your Doctor Isn't Watching

The standard lipid panel misses what actually predicts cardiovascular events. This guide covers the five markers that matter — and what to do when they're off.

No spam. One email with the PDF, nothing else.

What to Bring
  • 01Most recent comprehensive metabolic panel (CMP)
  • 02Lipid panel with LDL-P or ApoB if available
  • 03Thyroid panel (TSH, Free T3, Free T4) if relevant
  • 04Any prior A1C, fasting insulin, or glucose tolerance results